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Filtered Search Results
Apexbio Technology LLC 4-quinolinol 611-36-9 100mg
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4-Quinolinol (CAS 611-36-9) is a hydroxylated derivative of quinoline with demonstrated antimicrobial properties It exerts inhibitory effects on the growth of various intestinal bacteria suggesting interference with microbial viability or metabolic pathways Additionally 4-quinolinol has been utilized in research as a sacrificial scavenger for photogenerated reactive oxygen species supporting studies on oxidative stress and photochemical processes These features highlight its utility in microbiological research and investigations into oxidative mechanisms
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Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 1 MG
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PVD-06 is a selective PROTAC PTPN2 degrader with a DC50 of 217 nM. It induces PTPN2 degradation via a VHL-, ubiquitin, and proteasome-dependent pathway. PVD-06 can promote T cell activation and amplify IFN-γ-mediated anticancer activity, making it suitable for investigating PTPN2 in diseases such as leukemia and melanoma.
- Selective PROTAC PTPN2 degrader
- Induces PTPN2 degradation via VHL-, ubiquitin, and proteasome-dependent pathway
- Promotes T cell activation
- Amplifies IFN-γ-mediated anticancer activity
- Composed of a PTPN2 ligand, a linker, and a VHL ligand
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Medchemexpress LLC LM11A-31 25mg | 102562-74-3 | 243.35 g/mol | C12H25N3O2 | 25 MG
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LM11A-31 a non-peptide p75NTR (neurotrophin receptor p75) modulator is an orally active and potent proNGF (nerve growth factor) antagonist LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer s disease mouse models with mid- to late-stage disease progression[1][2]
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Medchemexpress LLC Pomalidomide-amido-c5-peg2-c6-chlorine | 1835705-69-5 | 98.75% | 594.10 | 25 MG
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Pomalidomide-amido-C5-PEG2-C6-chlorine is a derivative of Pomalidomide. It is intended for research use only and is not sold to patients. The compound has a molecular weight of 594.10 and a chemical formula of C29H40ClN3O8. It appears as a white to off-white solid. This compound is cited in research related to the modular design of PROTACs for the degradation of oncogenic BCR-ABL.
- It is a derivative of Pomalidomide.
- It is used for research purposes only.
- It is a solid with a white to off-white appearance.
- It has been utilized in studies concerning PROTAC design for degrading oncogenic BCR-ABL.
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Ambeed 1Methylpyrrolidine
1-Methylpyrrolidine, 120-94-5, 95%
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Medchemexpress LLC Pomalidomide-amido-C | 25MG
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Pomalidomide-amido-C | 25MG
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Medchemexpress LLC 5'-O-(4,4'-dimethoxytrityl)-5-methoxyuridine | 2095417-73-3 | 98.2% | 576.59 g·mol⁻¹ | C31H32N2O9 | 10 MG
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5'-O-(4,4'-Dimethoxytrityl)-5-methoxyuridine is a DMT-protected nucleoside derivative used as a building block in solid-phase oligonucleotide synthesis. The 4,4'-dimethoxytrityl (DMT) group protects the 5'-hydroxyl during stepwise chain assembly, enabling incorporation of 5-methoxyuridine into synthetic oligonucleotides for research applications.
- DMT-protected 5'-hydroxyl for stepwise synthesis.
- Designed for incorporation into oligonucleotides.
- High purity suitable for research use (98.2%).
- Molecular weight 576.59 g·mol⁻¹.
- Chemical formula C31H32N2O9.
- Supplied as a small-scale vial (10 mg).
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Sigma Aldrich Fine Chemicals Biosciences Ethyl 4 Ntrobenzoate Phar100MG
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
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Accela Chembio Inc 4-hydroxyquinoline | 25g | 611-36-9 | MFCD00006777 | 98% | Shelf Life: 1800 Days | Regular
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4-hydroxyquinoline | 25g | 611-36-9 | MFCD00006777 | 98% | Shelf Life: 1800 Days | Regular
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Medchemexpress LLC Ro 31-9790 (GI4747) | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 50 MG
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Ro 31-9790 is a synthetic matrix metalloproteinase (MMP) inhibitor used as a research reagent to probe MMP activity, protease-mediated ectodomain shedding, and related cellular pathways. It is supplied as a high-purity solid for laboratory studies and includes handling and storage recommendations to preserve stability.
- High purity, suitable for biochemical and cellular assays.
- Molecular weight 315.41 g/mol and formula C15H29N3O4 for compound identification.
- Off-white to light yellow solid appearance for easy visual confirmation.
- Recommended storage at 4°C; protect from light and store under inert gas; in solvent, store at -80°C (6 months) or -20°C (1 month).
- Soluble in DMSO with supplier-provided concentration guidance for assay preparation.
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Apexbio Technology LLC IAA-94 54197-31-8 5mg
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IAA-94 (CAS 54197-31-8) is a small-molecule inhibitor of epithelial chloride channels modulating cellular electrophysiological properties by disrupting chloride ion transport Experimental studies have demonstrated that IAA-94 can interfere with interactions involving the negative factor (Nef) protein during infection indicating its capacity to modulate Nef-mediated processes Due to its specificity in targeting chloride channels IAA-94 is widely utilized in investigations of ion channel-related signaling pathways in tumor cells and serves as a valuable tool in studies of cell electrophysiology and infection mechanisms
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TARGETMOL CHEMICALS INC 6-GNTI DIHYDROCHLORIDE 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. 6'-GNTI dihydrochloride is a (kappa)-opioid receptor (KOR) agonist that favors activation of G-protein-mediated signaling over recruitment of (beta)-aspirin 2. 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neurons. purity: 98%
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Ambeed 2S 5R 5 6Amino9Hpurin9yl tet
((2S,5R)-5-(6-Amino-9H-purin-9-yl)tetrahydrofuran-2-yl)methanol, 4097-22-7, 98%
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Ambeed 3Chloro4methoxybenzaldehyde
3-Chloro-4-methoxybenzaldehyde, 4903-09-7, 98%
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Ambeed S 3 4 2Chloro5iodobenzyl phen
(S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran, 915095-94-2, 97%
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